About two and a half years after Evolver.fm started taking Google to task over its lack of a super-simple wireless music solution along the lines of Apple?s AirPlay for zapping music to speakers around the house, Google unveiled on Wednesday what some are calling its answer to AirPlay: Chromecast.
Source: http://gizmodo.com/for-music-fans-google-chromecast-is-no-apple-airplay-900447846
guinea bissau google stock google stock china gdp dont trust the b in apartment 23 johnny damon kirk cameron
It seems like everywhere we look, a Redbox is there. If you could use a helping hand to find one though, now there's a Windows 8 app for that. Available today, the app assists in tracking down the nearest kiosk (our guess: outside your neighborhood's gas station), lets you reserve movies and games at the cardinal cabinets as well as watch trailers. An instant streaming app for the OS still hasn't surfaced, but we'd settle for an update that reminds us to return discs on time.
Filed under: HD
Source: Windows Store
Fidelity Charlie Strong Calendar 2013 john boehner HGTV Dream Home 2013 eric cantor eric cantor
SAN FRANCISCO (AP) -- Netflix's revival of the comedy series "Arrested Development" didn't reel in as many subscribers to the Internet video service as Wall Street had hoped, turning a solid second-quarter earnings report into a reality check.
Even though Netflix's profit more than quadrupled, the report released Monday flopped among investors because it didn't live up to the lofty expectations propelling the company's high-flying stock. The shares have nearly tripled since the beginning of the year, raising the pressure on Netflix Inc. to deliver spectacular numbers.
That didn't' happen during the three months ending in June, despite the much-anticipated return of "Arrested Development" after a seven-year absence. Netflix's stock slid $9.96, or nearly 4 percent, to $252 in extended trading after the numbers came out.
"It was a very good quarter by most standards, but that doesn't cut it when your stock has risen by 200 percent," said Pacific Crest analyst Andy Hargeaves.
Netflix picked up 630,000 U.S. subscribers during the three months ending in June. That performance was slightly above the mid-range target set by Netflix Inc.'s management in April. But the Los Gatos, Calif., company also had predicted it might end the period with as many as 880,000 more subscribers ? a goal that many investors evidently were hoping would be reached.
Expectations had been raised by the Memorial Day weekend release of 15 new "Arrested Development" episodes. The comedy starring Jason Bateman and Michael Cera had built a cult following before its cancellation by the Fox network in 2006, after three seasons on broadcast television.
In a letter to shareholders, Netflix CEO Reed Hastings credited "Arrested Development" for providing a "small but noticeable bump" in subscribers. He praised the company for being able to add more subscribers during the first half of this year than it did last year, despite intensifying competition from other Internet video services run by Amazon.com Inc. and Hulu.
Netflix has added 2.7 million subscribers so far this year, up from 2.5 million at the same time last year.
"We are feeling quite good about the business," Hastings assured investors during an unusual live video presentation that was akin to an Internet talk show. Two hosts, CNBC anchor Julia Boorstin and BTIG Research analyst Rich Greenfield, peppered Hastings and two other Netflix executives with questions that had been emailed and tweeted to them.
The second-quarter gains leave Netflix with 29.8 million U.S. subscribers to an $8 monthly service that streams video to Internet-connected devices.
Netflix also added 605,000 international subscribers in the second quarter to boost its total customers outside the U.S to 7.75 million.
Those figures, particularly the U.S. subscriber count, have become Wall Street's focal point, said Sterne Agee analyst Arvind Bhatia. "This is not about the earnings at this point," he said. "It's about how much of the market for Internet video that Netflix can grab."
Netflix's DVD-by-mail rental service continued a gradual demise as more people embrace the convenience of Internet streaming instead of waiting for discs to be delivered. Netflix lost another 475,000 DVD subscribers in the second quarter, leaving the company with 7.5 million on that side of its service. Netflix has been pushing people toward streaming because the company believes DVDs are destined for obsolescence and it doesn't want to spend a lot on the business any longer.
The company increasingly is relying on programming produced especially for its service to retain current subscribers and lure new customers. Since the beginning of the year, Netflix has released four original series, including the debut of "Orange Is The New Black" earlier this month.
During its first week on Netflix, "Orange Is The New Black" attracted more viewers than "Arrested Development" or the other two original series, "House of Cards" and "Hemlock Grove," released this year, according to Ted Sarandos, the company's chief content officer. He declined to provide any specifics about the audience's size.
Netflix received a major boost from "House of Cards," a political drama starring Kevin Spacey, during the opening three months of the year. That series earned nine Emmy Award nominations, including for outstanding drama, best actor and best actress. No Internet-only series had previously been nominated in those marquee categories.
"Arrested Development" also garnered three Emmy nominations.
No one was counting on "Arrested Development" to attract as many subscribers as the February release of "House of Cards" because the comedy came out during the second quarter, a period when Netflix has more trouble signing up new customers. That's because the longer daylight hours and the start of the summer vacation season translate into a smaller pool of people interested in subscribing to a video service.
"It was a very solid quarter," Hastings told The Associated Press in a Monday interview. "But we are focused on how do we get substantially bigger and how do we get substantially better. The quarter was fine, but it's not our main focus."
Netflix earned $29.5 million, or 49 cents per share, in the quarter, up from $6.2 million, or 11 cents per share, a year earlier.
Analysts surveyed by FactSet had forecast earnings of 40 cents per share.
Netflix's revenue climbed 20 percent from last year to $1.07 billion, mirroring analyst projections.
In the current quarter ending in September, Netflix predicted it will add 690,000 to 1.49 million U.S. subscribers.
Source: http://news.yahoo.com/netflixs-2q-report-flops-despite-222056142.html
ivan rodriguez planetary resources mothers day gift ideas natalee holloway scotty mccreery megan fox pregnant metta world peace suspension
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 22-Jul-2013
Share ] Contact: Ana Herrera
oic@uc3m.es
Carlos III University of Madrid
This news release is available in Spanish.
"A wave is a deformation in the surface of a liquid that moves at a speed that is independent of that liquid," the researchers explain. For example: in the waves that are formed when a rock is thrown into a pond, the water remains still while the waves move away from the center at their own speed. "In our case, what occurs is actually the opposite: the water moves very rapidly (at several meters per second), but the wave moves at a speed of zero. That is, it remains still, "frozen" in time for any observer who sees it from outside of the water," explains one of the authors of the research report, Javier Rodrguez, of UC3M's Fluids and Thermal Engineering Department.
Every surfer's dream
In this experiment, which is described in an article published in the journal Experiments in Fluids, the scientists used digital processing techniques and visualization techniques that used a laser to reconstruct the form of the wave in three dimensions in order to compare it with real waves, similar to those that are ridden by surfers. "The most remarkable thing is to observe a pipeline wave that remains still, to the point that we can put our fingers under the crest for as long as we want and not get wet, because this wave never breaks," describes Javier Rodrguez.
In order to recreate this phenomenon, the scientists constructed a small canal in a laboratory at the University. The prototype is relatively simple, they say: it consists of a semi-submerged panel with a square corner that partially obstructs the flow in a tank of water that is approximately the length of a van. "This is the simplest and cheapest way to produce different heights in a very rapidly moving current of water," states Professor Rodrguez.
In the theoretical part of the study, in which the UC3M scientists are currently collaborating with colleagues from UC San Diego (USA) and from the University of East Anglia (United Kingdom), they are using computer simulation techniques and asymptotic analysis to create an approximate description of this wave's formation. "This description is precise enough to enable us to understand its behavior; we are taking advantage of the fact that the wave is very slender. That is, as we move away from its starting point, its size slowly increases," points Pablo Martnez-Legazpi, a researcher at UC San Diego. "As we investigate further into this subject," he adds, "we realize that this formation process is representative of and common to other waves that are of great interest to civil and naval engineering, such as waves that crash into ports, bridges or off-shore oil rigs during rough sea conditions."
Structural and environmental applications Thanks to this experiment, it is possible to generate a wave that would never be static in Nature and to render it motionless in the laboratory for the time that is necessary to study it in detail. Understanding how these waves are formed can be tremendously useful when predicting the intensity of the streams that appear when waves impact against marine structures (ports, off-shore oil rigs, ships, etc.) and it could help to anticipate the damage that they might cause. In fact, this research was suggested and partially financed by the US Navy due to its implications for improvements in naval hydrodynamics.
From the oceanographic point of view, this is also a very useful tool, as it allows for the implementation of a great number of research techniques that would be very difficult to apply to a wave in motion. In addition, it has direct environmental applications: it allows for a better response to what occurs on the marine surface when a wave breaks, which in turn can help scientists understand how carbon dioxide exchange between the ocean and atmosphere occurs. "And although it has nothing to do with science, we also think this research can be of interest when it comes to creating decorative fountains or rides in water parks," notes Javier Rodrguez. "If, in addition to being interesting because it can help us understand the ocean, you can also have fun with it, why not do it?" he concludes.
###
Further information:
Title: Plunging to spilling transition in corner surface waves in the wake of a partially submerged vertical plate Authors: Martinez Legazpi, P; Rodriguez-Rodriguez, J; Marugan-Cruz, C; Lasheras, JC Journal: EXPERIMENTS IN FLUIDS. Volume: 54. Number: 1. Article number: 1437. DOI: 10.1007/s00348-012-1437-7. Published in January 2013.
http://www.youtube.com/watch?v=bp0SLNp2wUI
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 22-Jul-2013 Share ] Contact: Ana Herrera
oic@uc3m.es
Carlos III University of Madrid
This news release is available in Spanish.
"A wave is a deformation in the surface of a liquid that moves at a speed that is independent of that liquid," the researchers explain. For example: in the waves that are formed when a rock is thrown into a pond, the water remains still while the waves move away from the center at their own speed. "In our case, what occurs is actually the opposite: the water moves very rapidly (at several meters per second), but the wave moves at a speed of zero. That is, it remains still, "frozen" in time for any observer who sees it from outside of the water," explains one of the authors of the research report, Javier Rodrguez, of UC3M's Fluids and Thermal Engineering Department.
Every surfer's dream
In this experiment, which is described in an article published in the journal Experiments in Fluids, the scientists used digital processing techniques and visualization techniques that used a laser to reconstruct the form of the wave in three dimensions in order to compare it with real waves, similar to those that are ridden by surfers. "The most remarkable thing is to observe a pipeline wave that remains still, to the point that we can put our fingers under the crest for as long as we want and not get wet, because this wave never breaks," describes Javier Rodrguez.
In order to recreate this phenomenon, the scientists constructed a small canal in a laboratory at the University. The prototype is relatively simple, they say: it consists of a semi-submerged panel with a square corner that partially obstructs the flow in a tank of water that is approximately the length of a van. "This is the simplest and cheapest way to produce different heights in a very rapidly moving current of water," states Professor Rodrguez.
In the theoretical part of the study, in which the UC3M scientists are currently collaborating with colleagues from UC San Diego (USA) and from the University of East Anglia (United Kingdom), they are using computer simulation techniques and asymptotic analysis to create an approximate description of this wave's formation. "This description is precise enough to enable us to understand its behavior; we are taking advantage of the fact that the wave is very slender. That is, as we move away from its starting point, its size slowly increases," points Pablo Martnez-Legazpi, a researcher at UC San Diego. "As we investigate further into this subject," he adds, "we realize that this formation process is representative of and common to other waves that are of great interest to civil and naval engineering, such as waves that crash into ports, bridges or off-shore oil rigs during rough sea conditions."
Structural and environmental applications Thanks to this experiment, it is possible to generate a wave that would never be static in Nature and to render it motionless in the laboratory for the time that is necessary to study it in detail. Understanding how these waves are formed can be tremendously useful when predicting the intensity of the streams that appear when waves impact against marine structures (ports, off-shore oil rigs, ships, etc.) and it could help to anticipate the damage that they might cause. In fact, this research was suggested and partially financed by the US Navy due to its implications for improvements in naval hydrodynamics.
From the oceanographic point of view, this is also a very useful tool, as it allows for the implementation of a great number of research techniques that would be very difficult to apply to a wave in motion. In addition, it has direct environmental applications: it allows for a better response to what occurs on the marine surface when a wave breaks, which in turn can help scientists understand how carbon dioxide exchange between the ocean and atmosphere occurs. "And although it has nothing to do with science, we also think this research can be of interest when it comes to creating decorative fountains or rides in water parks," notes Javier Rodrguez. "If, in addition to being interesting because it can help us understand the ocean, you can also have fun with it, why not do it?" he concludes.
###
Further information:
Title: Plunging to spilling transition in corner surface waves in the wake of a partially submerged vertical plate Authors: Martinez Legazpi, P; Rodriguez-Rodriguez, J; Marugan-Cruz, C; Lasheras, JC Journal: EXPERIMENTS IN FLUIDS. Volume: 54. Number: 1. Article number: 1437. DOI: 10.1007/s00348-012-1437-7. Published in January 2013.
http://www.youtube.com/watch?v=bp0SLNp2wUI
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-07/ciuo-ase072213.php
mario manningham williams syndrome hoya casa de mi padre corned beef and cabbage diners drive ins and dives jeff who lives at home
WASHINGTON (AP) ? Parents are picking up less of their children's college costs while grants and scholarships now have the top role in paying the bills, according to a report released Tuesday by loan giant Sallie Mae.
Since the recession, more college-bound students have eliminated schools from their searches based on costs and have relied less on their parents once they get to campus, the report found. Worries such as tuition increases and job losses seem to have faded as the economy has improved, yet parents and students still make decisions on schools, majors and work schedules based on the price tag.
"We have moved into a post-recession reality in how people pay for college," said Sarah Ducich, Sallie Mae's senior vice president for public policy.
College spending was about $21,000 during 2012, down from a peak of $24,000 in 2010, according to the Sallie Mae-Ipsos Public Affairs report.
The annual survey of student financial aid found students earned about $6,300 in grants and scholarships to pay for college costs, taking the top spots from parents. Student loans were the third most common source to pick up the bill for courses, housing and books.
The average student borrowed $8,815 in federal loans.
The rate for those loans was the subject of debate in the Senate this week, as lawmakers consider a compromise that would offer some students lower rates for the next few years but would prescribe higher rates for future classes.
Last year, the average family turned to grants and scholarships to cover 30 percent of college costs. Parents' income and savings covered 27 percent of the bill and student borrowing covered 18 percent.
"Parents are willing to stretch themselves," Ducich said "It's not that they're willing to pay. It's that their income is not keeping up."
Parents' enthusiasm for college has not shriveled, though. The survey found 85 percent of parents saw college bills as an investment in their children's future.
"We're in a new normal where big ticket items like college, families will pay for them but won't stress about them too much," said Cliff Young, managing director at Ipsos.
One-fifth of parents added work hours to pay for college and half of students increased their work hours, too. The report found 57 percent of families said students were living at home or with relatives, up from 41 percent last year and 44 percent in 2011.
Among other strategies employed to deal with costs:
? One-fifth of students from low-income families chose to transfer to less expensive schools.
? About one-fifth of students also said they changed majors to fields that were expected to be more marketable upon graduation.
? In all, 67 percent of students and their families eliminated colleges at some stage during the application process because of costs, up from 58 percent in 2008.
"It forced them to adopt new behaviors of savings and ways to find nickels and dimes," Young said.
The tuition sticker price at public four-year colleges is up 27 percent beyond overall inflation over the last five years, according to the latest figures from a separate study from the College Board. This past year it rose nearly 5 percent to an average of $8,655 nationwide. Including room and board, the average sticker price at public colleges is now $17,860, and students pay on average $12,110. At private four-year colleges, the average full tuition price is now just under $40,000, with the average student paying $23,840.
What does that mean for the average college student?
About two-thirds of the national college class of 2011 had loan debt at graduation, and their debt averaged $26,600, according to the most recent figures from the California-based Institute for College Access and Success. That was an increase of about 5 percent from the class before them.
The Ipsos telephone poll was conducted between April 10 and May 9 with 1802 parents of 18 to 24-year-old undergraduate students and 800 undergraduate students aged 18 to 24. The survey has a margin of error of plus or minus 2.5 percentage points.
___
Follow Philip Elliott on Twitter: http://www.twitter.com/philip_elliott
Associated Pressneil armstrong little league world series us open tennis us open tennis Empire State Building shooting Republican National Convention Karlie Redd
Wearable Tech Expo
HzO, a leader in the field of thin film nano-coating for wearable technologies, will demonstrate its WaterBlock technology for commercial devices at the Wearable Technologies Conference 2013, held in San Francisco on July 22 and 23, and the Wearable Tech Expo, held in New York City on July 24 and 25.?The wearables industry has emerged as a strong market for HzO. Consumers, soldiers, first responders and sportsmen are among those who now have HzO protecting their wearable devices against all kinds of liquids, from water to sweat to corrosive agents?
HzO's proprietary WaterBlock technology is a thin film surface coating applied inside a device, creating a protective barrier. Using a chemical vapor deposition process, HzO covers vital electronic parts that are often compromised and tarnished by sudden or persistent exposure to corrosives -- including water, humidity and other liquids ? as well as contaminating particles.
HzO product demonstrations and information will be available during both conferences:
About HzO, Inc.
HzO is an industry leader in the field of thin film nano-coating technology. With its revolutionary and proprietary WaterBlock??vapor deposition process, HzO protects electronic devices from damage due to corrosives, water, and other liquids and small debris without the additional bulk, weight or change to aesthetics added by mechanical seals, gaskets, plugs, cases and covers. HzO is commercializing WaterBlock in consumer electronics, military, first responder devices, medical, industrial, automotive and other markets. Winner of the 2012 CES Innovations Design and Engineering Award and the Utah Innovation Award, HzO has been named one of the Top Ten Emerging Nano-Companies in the U.S. in each of the past two years.
Full Article
SUBSCRIBE TO MFRTech.COM TODAY, CUSTOMIZE YOUR NEWS, RECEIVE BY EMAIL (CLICK HERE)
For a Complete Version of this BUSINESS WIRE Press Release
Permission to Reproduce:
Unless otherwise stated, the copyright and similar rights to all material published on this website are owned by The Manufacturers Group Inc. DBA Manufacturing & Technology eJournal( mfrtech.com ). Reproduction of any article in print, electronic or any other form must acknowledge mfrtech.com as the Source and include a link to http://www.mfrtech.com
Source: http://www.mfrtech.com/articles/52880.html
Samsung Galaxy S4 St Francis Anquan Boldin Pope Benedict Jesuits percy harvin percy harvin
Public release date: 1-Jul-2013 Share ] Contact: Megan MacDonald
megan.macdonald@oregonstate.edu
541-737-3273
Oregon State University
CORVALLIS, Ore. Studies have shown that children with autism often struggle socially and now new research suggests that a corresponding lack of motor skills including catching and throwing may further contribute to that social awkwardness.
The findings, published in the July issue of Adapted Physical Activity Quarterly, add to the growing body of research highlighting the link between autism and motor skill deficits.
Lead author Megan MacDonald is an assistant professor in the College of Public Health and Human Sciences at Oregon State University. She is an expert on the movement skills of children with autism spectrum disorder.
In the study, researchers looked a group of young people ages 6 to 15 diagnosed with autism spectrum disorder. All 35 of the students were considered high-functioning and attended typical classrooms. The researchers looked at two types of motor skills "object-control" motor skills, which involve more precise action such as catching or throwing and "locomotion" skills, such as running or walking. Students who struggled with object-control motor skills were more likely to have more severe social and communication skills than those who tested higher on the motor skills test.
"So much of the focus on autism has been on developing social skills, and that is very crucial," MacDonald said. "Yet we also know there is a link between motor skills and autism, and how deficits in these physical skills play into this larger picture is not clearly understood."
Developing motor skills can be crucial for children because students often "mask" their inability to participate in basic physical activities. A student with autism may not be participating on the playground because of a lack of social skills, but the child may also be unsure of his or her physical ability to play in these activities.
"Something which seems as simple as learning to ride a bike can be crucial for a child with autism," MacDonald said. "Being able to ride a bike means more independence and autonomy. They can ride to the corner store or ride to a friend's house. Those kind of small victories are huge."
She said the ability to run, jump, throw and catch isn't just for athletic kids physical activity is linked not only to health, but to social skills and mental well-being.
"I often show people photos of what I like to do in my spare time canoeing, hiking, snowshoeing, and then point out that these require relatively proficient motor skills," she said. "But that is not why I do those things. I'm doing it because I'm with my friends and having fun."
MacDonald said the positive news for parents and educators is that motor skills can be taught.
"We have programs and interventions that we know work, and have measurable impact on motor skill development," MacDonald said. "We need to make sure we identify the issue and get a child help as early as possible."
###
This study was coauthored by Catherine Lord of Weill Cornell Medical College and Dale Ulrich of the University of Michigan.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 1-Jul-2013 Share ] Contact: Megan MacDonald
megan.macdonald@oregonstate.edu
541-737-3273
Oregon State University
CORVALLIS, Ore. Studies have shown that children with autism often struggle socially and now new research suggests that a corresponding lack of motor skills including catching and throwing may further contribute to that social awkwardness.
The findings, published in the July issue of Adapted Physical Activity Quarterly, add to the growing body of research highlighting the link between autism and motor skill deficits.
Lead author Megan MacDonald is an assistant professor in the College of Public Health and Human Sciences at Oregon State University. She is an expert on the movement skills of children with autism spectrum disorder.
In the study, researchers looked a group of young people ages 6 to 15 diagnosed with autism spectrum disorder. All 35 of the students were considered high-functioning and attended typical classrooms. The researchers looked at two types of motor skills "object-control" motor skills, which involve more precise action such as catching or throwing and "locomotion" skills, such as running or walking. Students who struggled with object-control motor skills were more likely to have more severe social and communication skills than those who tested higher on the motor skills test.
"So much of the focus on autism has been on developing social skills, and that is very crucial," MacDonald said. "Yet we also know there is a link between motor skills and autism, and how deficits in these physical skills play into this larger picture is not clearly understood."
Developing motor skills can be crucial for children because students often "mask" their inability to participate in basic physical activities. A student with autism may not be participating on the playground because of a lack of social skills, but the child may also be unsure of his or her physical ability to play in these activities.
"Something which seems as simple as learning to ride a bike can be crucial for a child with autism," MacDonald said. "Being able to ride a bike means more independence and autonomy. They can ride to the corner store or ride to a friend's house. Those kind of small victories are huge."
She said the ability to run, jump, throw and catch isn't just for athletic kids physical activity is linked not only to health, but to social skills and mental well-being.
"I often show people photos of what I like to do in my spare time canoeing, hiking, snowshoeing, and then point out that these require relatively proficient motor skills," she said. "But that is not why I do those things. I'm doing it because I'm with my friends and having fun."
MacDonald said the positive news for parents and educators is that motor skills can be taught.
"We have programs and interventions that we know work, and have measurable impact on motor skill development," MacDonald said. "We need to make sure we identify the issue and get a child help as early as possible."
###
This study was coauthored by Catherine Lord of Weill Cornell Medical College and Dale Ulrich of the University of Michigan.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-07/osu-cwd062813.php
andrew bird lizzie borden lizzie borden iona taylor allderdice mixtape andrew bogut monta ellis
July 1, 2013 ? The Alzheimer's Association projects that the number of people living with Alzheimer's disease will soar from 5 million to 13.8 million by 2050 unless scientists develop new ways to stop the disease. Current medications do not treat Alzheimer's or stop it from progressing; they only temporarily lessen symptoms, such as memory loss and confusion.
Current Alzheimer's drugs aim to reduce the amyloid plaques -- sticky deposits that build up in the brain--that are a visual trademark of the disease. The plaques are made of long fibers of a protein called Amyloid ?, or A?. Recent studies, however, suggest that the real culprit behind Alzheimer's may be small A? clumps called oligomers that appear in the brain years before plaques develop.
In unraveling oligomers' molecular structure, UCLA scientists discovered that A? has a vastly different organization in oligomers than in amyloid plaques. Their finding could shed light on why Alzheimer's drugs designed to seek out amyloid plaques produce zero effect on oligomers.
The UCLA study suggests that recent experimental Alzheimer's drugs failed in clinical trials because they zero in on plaques and do not work on oligomers. Future studies on oligomers will help speed the development of new drugs specifically aiming at A? oligomers.
The study was published as Paper of the Week in the June 28 issue of the peer-reviewed Journal of Biological Chemistry.
Share this story on Facebook, Twitter, and Google:
Other social bookmarking and sharing tools:
Story Source:
The above story is reprinted from materials provided by University of California, Los Angeles (UCLA), Health Sciences, via Newswise.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Note: If no author is given, the source is cited instead.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/_yAQ_kmv_80/130701100602.htm
angelman syndrome total recall troy tulowitzki katie couric good morning america the rock vs john cena acm awards 2012 january jones
by Jian Ping
CHICAGO, June 29 (Xinhua) -- With drumbeat and lion dances, a local Chinese culture organization celebrated its expansion of services on Chinese arts in downtown Chicago Saturday afternoon.
Xilin Association, headquartered in western suburb of Chicago, has recently launched the Performing Arts Academy in Chicago. The group offers education programs, arts classes and other social services to local community.
"I've been involved with Xilin's activities for more than 10 years and witnessed its growth step by step," said Kitty Wo, executive director of the newly opened Performing Arts Academy.
Wo said the academy will offer courses in dance, music and arts. "We want to enrich the educational experience of children and adults," she said.
Among the VIPs and community leaders who praised Xilin's services in the Asian community and American society at the opening ceremony are Illinois Secretary of State Jessie White, Chinese Deputy General Consul in Chicago Wang Yong and a representative sent by U.S. Senator Mark Kirk.
"It's important for us to support an institution like Xilin, a place where people can come and learn about the Chinese culture and for the young to learn artistic skills," White said.
Xilin was set up as a Chinese language school in 1989 when Linda Yang, its executive director, and a couple of other Chinese parents couldn't find a school to send their children to learn simplified Chinese. They organized their own school, utilizing the facility at the University of Illinois at Chicago (UIC) to provide lessons. The program was so well received that it was included as a special program at the Chancellor's Office at UIC.
In 1991, Under Yang's leadership, the group set up its office and a Chinese language school in a western suburb of Chicago - Naperville, where there was a large Chinese population.
They soon realized that a language school can't meet the needs of the students, Yang said. So Xilin set up an affiliation with a community college and began offering classes in English and Math.
Over the years, the Xilin Association has expanded the children's education program from weekend schooling to after school programs, and added performing arts, senior services and community healthy programs.
"Xilin's social service to seniors was great," Bill Liu, a longtime supporter and board member of Xilin told Xinhua. "It provides a venue for seniors who don't speak English to have social activities together."
The organization provides services for people from age three to 103, Yang said. "Not just Chinese, but also people from other ethnic backgrounds."
Xilin's senior services include therapeutic activities, meals and social activities. Their community health programs provide mammogram, osteoporosis and hepatitis B screenings for people over 40 who have no insurance coverage.
With the grand opening of the Performing Arts Academy, two dance classes, one for children under seven, and the other, which opens to all ages, have started.
Source: http://english.sina.com/culture/2013/0629/603908.html
Ben Wilson Latest Presidential Polls trump presidential debate debate marco scutaro Russell Means
Sorry, Readability was unable to parse this page for content.
Source: http://www.facebook.com/newschannel3/posts/10151429460761146
What is a Jesuit pi day Samsung Galaxy S4 St Francis Anquan Boldin Pope Benedict Jesuits
?Rahm would not want to repeat the situation that Rich had when he was dealing with the Children's Museum,? Houlihan said, referring to former Mayor Richard M. Daley's now-reversed decision to ram through a new Children's Museum in Grant Park over the?...
barry sanders barry sanders jimmie johnson juan pablo montoya crash chardon high school shooting mark martin cleveland news
June 30, 2013 ? Anyone who's ever heard a Beethoven sonata or a Beatles song knows how powerfully sound can affect our emotions. But it can work the other way as well -- our emotions can actually affect how we hear and process sound. When certain types of sounds become associated in our brains with strong emotions, hearing similar sounds can evoke those same feelings, even far removed from their original context. It's a phenomenon commonly seen in combat veterans suffering from post-traumatic stress disorder (PTSD), in whom harrowing memories of the battlefield can be triggered by something as common as the sound of thunder. But the brain mechanisms responsible for creating those troubling associations remain unknown. Now, a pair of researchers from the Perelman School of Medicine at the University of Pennsylvania has discovered how fear can actually increase or decrease the ability to discriminate among sounds depending on context, providing new insight into the distorted perceptions of victims of PTSD.
Their study is published in Nature Neuroscience.
"Emotions are closely linked to perception and very often our emotional response really helps us deal with reality," says senior study author Maria N. Geffen, PhD, assistant professor of Otorhinolaryngology: Head and Neck Surgery and Neuroscience at Penn. "For example, a fear response helps you escape potentially dangerous situations and react quickly. But there are also situations where things can go wrong in the way the fear response develops. That's what happens in anxiety and also in PTSD -- the emotional response to the events is generalized to the point where the fear response starts getting developed to a very broad range of stimuli."
Geffen and the first author of the study, Mark Aizenberg, PhD, a postdoctoral researcher in her laboratory, used emotional conditioning in mice to investigate how hearing acuity (the ability to distinguish between tones of different frequencies) can change following a traumatic event, known as emotional learning. In these experiments, which are based on classical (Pavlovian) conditioning, animals learn to distinguish between potentially dangerous and safe sounds -- called "emotional discrimination learning." This type of conditioning tends to result in relatively poor learning, but Aizenberg and Geffen designed a series of learning tasks intended to create progressively greater emotional discrimination in the mice, varying the difficulty of the task. What really interested them was how different levels of emotional discrimination would affect hearing acuity -- in other words, how emotional responses affect perception and discrimination of sounds. This study established the link between emotions and perception of the world -- something that has not been understood before.
The researchers found that, as expected, fine emotional learning tasks produced greater learning specificity than tests in which the tones were farther apart in frequency. As Geffen explains, "The animals presented with sounds that were very far apart generalize the fear that they developed to the danger tone over a whole range of frequencies, whereas the animals presented with the two sounds that were very similar exhibited specialization of their emotional response. Following the fine conditioning task, they figured out that it's a very narrow range of pitches that are potentially dangerous."
When pitch discrimination abilities were measured in the animals, the mice with more specific responses displayed much finer auditory acuity than the mice who were frightened by a broader range of frequencies. "There was a relationship between how much their emotional response generalized and how well they could tell different tones apart," says Geffen. "In the animals that specialized their emotional response, pitch discrimination actually became sharper. They could discriminate two tones that they previously could not tell apart."
Another interesting finding of this study is that the effects of emotional learning on hearing perception were mediated by a specific brain region, the auditory cortex. The auditory cortex has been known as an important area responsible for auditory plasticity. Surprisingly, Aizenberg and Geffen found that the auditory cortex did not play a role in emotional learning. Likely, the specificity of emotional learning is controlled by the amygdala and sub-cortical auditory areas. "We know the auditory cortex is involved, we know that the emotional response is important so the amygdala is involved, but how do the amygdala and cortex interact together?" says Geffen. "Our hypothesis is that the amygdala and cortex are modifying subcortical auditory processing areas. The sensory cortex is responsible for the changes in frequency discrimination, but it's not necessary for developing specialized or generalized emotional responses. So it's kind of a puzzle."
Solving that puzzle promises new insight into the causes and possible treatment of PTSD, and the question of why some individuals develop it and others subjected to the same events do not. "We think there's a strong link between mechanisms that control emotional learning, including fear generalization, and the brain mechanisms responsible for PTSD, where generalization of fear is abnormal," Geffen notes. Future research will focus on defining and studying that link.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/Wq0G_0EHIi4/130630145002.htm
academy award winners best picture 2012 oscar winners channel 3 news j lo j lo sacha baron cohen ryan seacrest
WASHINGTON (AP) ? The former director of the CIA and National Security Agency says the government should release more information about its secretive surveillance programs to reassure Americans that their privacy rights are being protected.
Michael Hayden said Sunday he believes the public will be more comfortable with the programs that gather phone and Internet records from around the world if people know more about how they are carried out and why.
Hayden also defended a secret court that approves government requests to gather the records. Critics say the Foreign Intelligence Surveillance Court has served as a rubber stamp to the requests instead of challenging government attorneys on whether the information is needed or gathered properly.
Hayden is now a security consultant and university professor. His comment came on CBS' "Face The Nation."
Associated Presssheree whitfield weather dallas pat summitt real housewives of atlanta colton bo ryan the last waltz
